Recombinant Human Cofilin 2 His Protein

Name: Recombinant Human Cofilin 2 His Protein
Brand: Novus Biologicals
SKU: NBP1-72427
Price: 929 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-72427

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all Cofilin 2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-166 of Human Cofilin 2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MASGVTVNDE VIKVFNDMKV RKSSTQEEIK KRKKAVLFCL SDDKRQIIVE EAKQILVGDI GDTVEDPYTS FVKLLPLNDC RYALYDATYE TKESKKEDLV FIFWAPESAP LKSKMIYASS KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKLGGNVVVS LEGKPL

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

20.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Cofilin 2 His Protein

SDS-PAGE: Recombinant Human Cofilin 2 His Protein [NBP1-72427]

SDS-Page: Recombinant Human Cofilin 2 Protein [NBP1-72427] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-72427

Formulation	20 mM Tris-HCl buffer (pH 8.0), 2 mM DTT, 10% glycerol, 50 mM Nacl
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cofilin 2

CFL2 protein belongs to the actin-binding proteins ADF family that contains 1 ADF-H domain. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. Defects in CFL2 are the cause of nemaline myopathy type 7 (NEM7). Recombinant human CFL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

cofilin 2 (muscle), Cofilin, muscle isoform, cofilin-2, NEM7

Gene Symbol

CFL2

Additional Cofilin 2 Products

Product Documents for Recombinant Human Cofilin 2 His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human Cofilin 2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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