Colivelin

Catalog # Availability Size / Price Qty
3945/500U
Colivelin
1 Image
Description: STAT3 activator; also protects against β-amyloid neurotoxicity
Product Details
Citations (1)
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Biological Activity

Neuroprotective peptide and activator of STAT3. Protects neurons against the neurotoxic effects of amyloid β-peptide (1-43) at a concentration of 100 fM in vitro. Suppresses neuronal death by activating STAT3 in vitro; upregulates cholinergic transmission and ameliorates memory impairment in Alzheimer's disease (AD) models. Also prevents alcohol-induced apoptosis in a fetal mouse model. Brain penetrant.

Technical Data

M.Wt:
2645.13
Formula:
C119H206N32O35
Sequence:
SALLRSIPAPAGASRLLLLTGEIDLP
Solubility:
Soluble to 1 mg/ml in 20% ethanol / water
Storage:
Store at -20°C
CAS No:
867021-83-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for Colivelin

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