Water-soluble carbon monoxide-releasing molecule. Suppresses thrombin-induced nitrite release in BV-2 microglia. Protects isolated rats hearts from reperfusion damage in vitro
and is cardioprotective in a rat myocardial infarction model in vivo
. Also prolongs survival of transplanted hearts in mice. Exhibits anti-inflammatory and vasorelaxant effects.
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Modulation of thrombin-induced neuroinflammation in BV-2 microglia by carbon monoxide-releasing molecule 3.
Bani-Hani et al.
Acute myocardial infarction in streptozotocin-induced hyperglycaemic rats: protection by a carbon monoxide-releasing molecule (CORM-3).
Filippo et al.
Naunyn Schmiedebergs Arch.Pharmacol., 2012;385:137
Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule.
Clark et al.
Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule.
Foresti et al.
Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages.
Sawle et al.