CP 465022 hydrochloride

Catalog # Availability Size / Price Qty
2932/10
2932/50
CP 465022 hydrochloride | CAS No. 1785666-59-2 | AMPA Receptor Antagonists
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Description: Selective and non-competitive AMPA antagonist

Chemical Name: 3-(2-Chlorophenyl)-2-[2-[6-[(diethylamino)methyl]-2-pyridinyl]ethenyl]-6-fluoro-4(3H)-quinazolinone hydrochloride

Purity: ≥99%

Product Details
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Biological Activity

Selective, non-competitive AMPA antagonist (IC50 = 25 nM in rat cortical neurons) that displays potent anticonvulsant activity. Also significantly blocks the persistent component of Nav1.6 channel activity. Brain penetrant and orally active.

Technical Data

M.Wt:
499.41
Formula:
C26H24ClFN4O.HCl
Solubility:
Soluble to 10 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
1785666-59-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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