CP 93129 dihydrochloride

Tocris Bioscience | Catalog # 1032

5-HT1B agonist
Tocris Bioscience

Key Product Details

Description

5-HT1B agonist
View all 5-HT1B Receptor Agonists »

Product Description

CP 93129 dihydrochloride is a potent and highly selective 5-HT1B agonist (Ki values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT1B, 5-HT1D, 5-HT1A, 5-HT1c and 5-HT2, respectively). Reduces food intake and decreases body weight in rats.

Licensing Information

Sold for research purposes under agreement from Pfizer Inc.

Product Specifications for CP 93129 dihydrochloride

Molecular Weight

288.18

Formula

C12H13N3O.2HCl

Storage

Desiccate at RT

Chemical Name

1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride

CAS Number

879089-64-2

PubChem ID

46927988

InChI Key

FLVJHUZZKVJQNH-UHFFFAOYSA-N

SMILES

Cl.Cl.O=C1NC2=C(NC=C2C2=CCNCC2)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 28.82 100
DMSO 28.82 100

Preparing Stock Solutions for CP 93129 dihydrochloride

The following data is based on the product molecular weight 288.18.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.47 mL 17.35 mL 34.70 mL
5 mM 0.69 mL 3.47 mL 6.94 mL
10 mM 0.35 mL 1.74 mL 3.47 mL
50 mM 0.07 mL 0.35 mL 0.69 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 17 publications citing the usage of this product.

Product Documents for CP 93129 dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CP 93129 dihydrochloride

For research use only

Citations for CP 93129 dihydrochloride

Customer Reviews for CP 93129 dihydrochloride (3)

3.7 out of 5
3 Customer Ratings
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  • Modulation of spontaneous interneuronal signalling
    Name: Sergiy Sylantyev
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: Arcuate nucleus
    Verified Customer | Posted 12/10/2023
    CP 93129 was used to modulate spontaneous generation of action potentials in neurons of arcuate nucleus. Illustration: application of 100 nM CP 93129 (grey bar) decreases frequency of AP generation in living neuron.
    CP 93129 dihydrochloride 1032
  • 5-HT has a potential for relaxant
    Name: Anonymous
    Species: Rat
    Assay Type: In Vivo
    Verified Customer | Posted 02/18/2020
    CP93129 (5-HT1B) 10nM
    CP 93129 dihydrochloride 1032
  • Antidepressantsby Cholecystokinin Neurons of the Dentate Gyrus
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 02/03/2020
    CP (10mM)
    CP 93129 dihydrochloride 1032

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