Potent and highly selective 5-HT1B
values are 8.1, 1100, 1500, 2900 and 7200 nM for 5-HT1B
, respectively). Reduces food intake and decreases body weight in rats.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold for research purposes under agreement from Pfizer Inc.
Modulation of neurotransmission by GPCRs is dependent upon the microarchitecture of the primed vesicle complex.
Hamid et al.
J Neurosci., 2014;34:260
Infusion of the serotonin1B (5-HT1B) agonist CP-93,129 into the parabrachial nucleus potently and selectively reduces food intake in rats.
Lee et al.
Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253.
Koe et al.
Drug Development Research, 1992;26:241
The citations listed below are publications that use Tocris products. Selected citations for CP 93129 dihydrochloride include:
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