Recombinant Human CRIF1 His Protein

Novus Biologicals | Catalog # NBP1-72519

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
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Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 48-222 of Human CRIF1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MPRWQLGPRY AAKQFARYGA ASGVVPGSLW PSPEQLRELE AEEREWYPSL ATMQESLRVK QLAEEQKRRE REQHIAECMA KMPQMIVNWQ QQQRENWEKA QADKERRARL QAEAQELLGY QVDPRSARFQ ELLQDLEKKE RKRLKEEKQK RKKEARAAAL AAAVAQDPAA SGAPSS

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

22.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human CRIF1 His Protein

SDS-PAGE: Recombinant Human CRIF1 His Protein [NBP1-72519]

SDS-PAGE: Recombinant Human CRIF1 His Protein [NBP1-72519]

SDS-Page: Recombinant Human CRIF1 Protein [NBP1-72519] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-72519
Formulation 20 mM Tris-HCl buffer (pH 8.0), 40% glycerol, 2 mM DTT, 0.2 M NaCl
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CRIF1

GADD45GIP1, also known as CRIF1, is a nuclear protein that plays a role in apoptosis control. This protein is expressed in a variety of tissues, including heart, thyroid, trachea, kidney, ovary, pancreas, testis and stomach. It functions as a negative regulator of G1 to S phase cell cycle production, specifically by working with GADD45 proteins to inhibit the activity of cyclin-dependent kinases. Recombinant human GADD45GIP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

CKBBP2, CKII beta-associating protein, CR6 interacting factor 1, CRIF1p53-responsive gene 6 protein, growth arrest and DNA damage-inducible proteins-interacting protein 1, growth arrest and DNA-damage-inducible, gamma interacting protein 1, MGC4667, MGC4758, papillomavirus L2 interacting nuclear protein 1, Papillomavirus L2-interacting nuclear protein 1, PLINP1, PLINP-1CKII beta binding protein 2, PRG6CR6-interacting factor 1

Gene Symbol

GADD45GIP1

Additional CRIF1 Products

Product Documents for Recombinant Human CRIF1 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human CRIF1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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