) channel opener. Relaxes rabbit isolated portal vein with an IC
value of 21 nM. Potent, orally active and hypotensive
Active Enantiomer also available.
16H 18N 2O 3
Soluble to 20 mM in DMSO
Store at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold under license
Other Product-Specific Information:
The potassium channel opener cromakalim (BRL 34915) activates ATP-dependent K + channels in isolated cardiac myocytes.
Escande et al.
Cromakalim, a potassium channel activator: a comparison of its cardiovascular haemodynamic profile and tissue specificity with those of pinacidil and nicorandil.
Longman et al.
Comparative effects of K + channel blockade on the vasorelaxant activity of cromakalim, pinacidil and nicorandil.
Wilson et al.
The citations listed below are publications that use Tocris products. Selected citations for Cromakalim include:
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