Cultrex Poly-D-Lysine

Poly-amino solution that promotes cell adhesion
Catalog # Availability Size / Price Qty

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Product Details
Citations (4)

Cultrex Poly-D-Lysine Summary

Cultrex Poly-D-Lysine is a poly-amino acid solution that is provided ready-to-use at a concentration 0.01%.

Key Benefits

• Promotes the proliferation and differentiation of a variety of neuronal cell lines
• Facilitates cell adhesion on tissue culture-treated plastic or glass surfaces
• Contains polymers in the 70,000-150,000 Da range
• Provided in phosphate-buffered saline (PBS)

Why Use Cultrex Poly-D-Lysine?

Poly-D-Lysine, a highly positively charged synthetic amino acid chain, is commonly used as a coating agent to promote cell adhesion in culture on tissue culture-treated plastic or glass surfaces. Moreover, poly-D-Lysine is resistant to enzymatic degradation and promotes the proliferation and differentiation of a variety of neuronal cell lines. This solution contains polymers in the 70,000-150,000 Da range, and it is provided sterile filtered and ready to use at 0.01%.


Protein Concentration
0.1 mg/mL
Endotoxin Level
≤ 20 EU/mL by Limulus Amoebocyte Lysate (LAL) assay
Sterility Testing
No bacterial or fungal growth detected following 14 days in culture
Testing Cell Culture
Supports attachment of rat PC-12 pheochromocytoma cells.
Product is stable for at least 3 months from the date of receipt when stored at 2-8 °C. Keep sterile.
Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended on the product label.
Store the unopened product at 2 - 8 °C.


For research use only. Not for diagnostic use.

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Citations for Cultrex Poly-D-Lysine

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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  1. Characterization of PARP6 Function in Knockout Mice and Patients with Developmental Delay
    Authors: A Vermehren-, JY Huang, M Levinson, MB Pomaville, S Reed, GA Bellus, F Gilbert, B Keren, D Heron, D Haye, C Janello, C Makowski, K Danhauser, LM Fedorov, TB Haack, KM Wright, MS Cohen
    Cells, 2021;10(6):.  2021
  2. Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning
    Authors: P Mergenthal, S Hariharan, JM Pemberton, C Lourenco, LZ Penn, DW Andrews
    PLoS computational biology, 2021;17(2):e1008630.  2021
  3. Expression of IL-20 Receptor Subunit beta Is Linked to EAE Neuropathology and CNS Neuroinflammation
    Authors: JR Dayton, Y Yuan, LP Pacumio, BG Dorflinger, SC Yoo, MJ Olson, SI Hernández-, MM McMahon, L Cruz-Oreng
    Frontiers in Cellular Neuroscience, 2021;15(0):683687.  2021
  4. Neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucoma.
    Authors: Stankowska D, Minton A, Rutledge M, Mueller B, Phatak N, He S, Ma H, Forster M, Yorio T, Krishnamoorthy R
    Invest Ophthalmol Vis Sci, 2015;56(2):893-907.  2015


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