CX 614
Chemical Name: 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one
Purity: ≥99%
Biological Activity
CX 614 is an AMPAkine; positive allosteric modulator of AMPA. Prototypical benzamide which occupies subsite A only. Modulates channel deactivation and desensitization.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Background References
-
Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy.
Harms et al.
Neuropharmacology, 2013;64:45 -
Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation.
Timm et al.
Mol.Pharmacol., 2011;80:267 -
Stable expression of recombinant AMPA receptor subunits: binding affinities and effects of allosteric modulators.
Hennegriff et al.
J.Neurochem., 1997;68:2424
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for CX 614
There are currently no reviews for this product. Be the first to review CX 614 and earn rewards!
Have you used CX 614?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
