CXCL1/GRO alpha/KC/CINC-1 Antibody (DMC499) - Chimeric

Novus Biologicals | Catalog # NBP3-48375

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Human IgG1 Clone # DMC499
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Product Specifications

Immunogen

CXCL1/GRO alpha/KC/CINC-1 recombinant protein expressed in mammalian cells (Accession# P09341). The exact amino acid sequence is proprietary.

Clonality

Monoclonal

Host

Human

Isotype

IgG1

Description

This product is shipped at ambient temperature. Store at -20C to -80C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80C (Avoid repeated freezing and thawing).

Scientific Data Images for CXCL1/GRO alpha/KC/CINC-1 Antibody (DMC499) - Chimeric

CXCL1/GRO alpha/KC/CINC-1 Antibody (DMC499) - Chimeric

Flow Cytometry: CXCL1/GRO alpha/KC/CINC-1 Antibody (DMC499) - Chimeric [NBP3-48375]

Flow cytometry analysis with Anti-CXCL1/GRO alpha/KC/CINC-1/GRO alpha/KC/CINC-1 (DMC499) on HEK293 cells transfected with human CXCL1/GRO alpha/KC/CINC-1/GRO alpha/KC/CINC-1 (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram), and Isotype antibody on HEK293 transfected with irrelevant protein (Orange histogram).

Applications for CXCL1/GRO alpha/KC/CINC-1 Antibody (DMC499) - Chimeric

Application
Recommended Usage

Flow Cytometry

1:100

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Advanced Features

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Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified from cell culture supernatant

Reconstitution

Dissolve the lyophilized antibody in sterile and low endotoxin water. The recommend volume of water is lot specific. Please refer to the instructions printed on the product vial or contact technical support.

Formulation

PBS, pH 7.4, 5-8% Trehalose

Preservative

Trehalose

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C in powder form. Store at -80C once reconstituted.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: CXCL1/GRO alpha/KC/CINC-1

CXCL1/GRO alpha/KC/CINC-1 is an ELR+ angiogenic chemokine that interacts with CXCR2/IL-8 RB to attract and activate neutrophils. It is produced at sites of microbial infection by macrophages, monocytes, Kupffer cells, hepatocytes, endothelial and epithelial cells, cardiac and vascular smooth muscle cells, fibroblasts, melanocytes,  mast cells, and neurons. CXCL1 function is associated with the development and extent of atherosclerosis, Alzheimer’s disease, and tumor angiogenesis.

Alternate Names

CINC-1, CINC1, GRO alpha, KC, MGSA-alpha

Gene Symbol

CXCL1

Additional CXCL1/GRO alpha/KC/CINC-1 Products

Product Documents for CXCL1/GRO alpha/KC/CINC-1 Antibody (DMC499) - Chimeric

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CXCL1/GRO alpha/KC/CINC-1 Antibody (DMC499) - Chimeric

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for CXCL1/GRO alpha/KC/CINC-1 Antibody (DMC499) - Chimeric

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  • Q: Are mouse or rat CXCL8/IL-8 products offered?

    A: Mouse and rat do not have a gene which encodes CXCL8/IL-8. In mouse, the functional homologs to human CXCL8/IL-8 are CXCL1/KC and CXCL2/MIP-2. In rat, the functional homolog to CXCL8/human IL-8 is CXCL3/CINC-2.

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