Recombinant Virus CXCL2/GRO beta/MIP-2/CINC-3 Protein

Novus Biologicals | Catalog # NBP2-35318

Novus Biologicals
100% Guarantee

Key Product Details

Source

E. coli

Accession Number

Q98157

Applications

Bioactivity, SDS-PAGE
View all CXCL2/GRO beta/MIP-2/CINC-3 Proteins and Enzymes »

Product Specifications

Description

A single, non-glycosylated polypeptide chain containing 70 amino acids corresponding to CXCL2/GRO beta/MIP-2/CINC-3 Source: E. coli

Uniprot ID: Q98157

Amino Acid Sequence: LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA

Purity

> 97 % pure by SDS-PAGE and HPLC

Endotoxin Level

Less than 1 EU/ug of CXCL2/GRO beta/MIP-2/CINC-3 as determined by LAL method.

Predicted Molecular Mass

8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Activity

CXCL2 Protein is fully biologically active when compared to standard. The specific activity is determined by the inhibitory effect on monocyte migration response to human MIP-1 alpha using a concentration range of 1.0ug-10.0ug/ml of viral MIP-2 will inhibit 25ng/ml of human MIP-1 alpha.

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation, and Storage

NBP2-35318
Formulation Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 7.4, 150mM NaCl.
Preservative No Preservative
Concentration Lyoph
Reconstitution Recommended to centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/mL.
Format Carrier-Free
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20 to -70C as supplied. After reconstitution, store at 2 to 8C for 1 month and at -20 to -70C for long term storage. Avoid repeated freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background: CXCL2/GRO beta/MIP-2/CINC-3

Viral MIP-2 is one of the three chemokine-like proteins expressed by the human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus, KSHV) and the other is ViMIP-1 and ViMIP-3. It shares 41 % and 48 % with human MIP-1alpha and ViMIP-1, respectively. Viral CXCL2 (MIP-2) has been shown to have antagonist activity towards a wide range of chemokine receptors and has functions of blocking infection by several different human immunodeficiency virus type 1 (HIV-1) strains. It may form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions. Additionally, Viral MIP-2 has been shown to activate and chemoattract human eosinphils.

Alternate Names

CINC-3, CINC3, GRO beta, MGSA-beta, MIP-2, Macrophage Inflammatory Protein, Macrophage Inflammatory Protein 2

Gene Symbol

CXCL2

UniProt

Q98157

Additional CXCL2/GRO beta/MIP-2/CINC-3 Products

Product Documents for Recombinant Virus CXCL2/GRO beta/MIP-2/CINC-3 Protein

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Recombinant Virus CXCL2/GRO beta/MIP-2/CINC-3 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Customer Reviews for Recombinant Virus CXCL2/GRO beta/MIP-2/CINC-3 Protein

There are currently no reviews for this product. Be the first to review Recombinant Virus CXCL2/GRO beta/MIP-2/CINC-3 Protein and earn rewards!

Have you used Recombinant Virus CXCL2/GRO beta/MIP-2/CINC-3 Protein?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs for Recombinant Virus CXCL2/GRO beta/MIP-2/CINC-3 Protein

Showing  1 - 1 of 1 FAQ Showing All

  • Q: Are mouse or rat CXCL8/IL-8 products offered?

    A: Mouse and rat do not have a gene which encodes CXCL8/IL-8. In mouse, the functional homologs to human CXCL8/IL-8 are CXCL1/KC and CXCL2/MIP-2. In rat, the functional homolog to CXCL8/human IL-8 is CXCL3/CINC-2.

Showing  1 - 1 of 1 FAQ Showing All
View all FAQs for Proteins and Enzymes