Cyclic AMP Antibody (9H4C4)

Novus Biologicals | Catalog # NBP1-51543

Novus Biologicals
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Key Product Details

Species Reactivity

Non-species specific

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 9H4C4
View all Cyclic AMP Primary Antibodies »

Product Specifications

Immunogen

Cyclic AMP, conjugated to KLH.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Cyclic AMP Antibody (9H4C4)

Application
Recommended Usage

ELISA

1:10000

Formulation, Preparation, and Storage

Purification

Ascites

Formulation

Ascites

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cyclic AMP

Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery

Alternate Names

3' 5' cyclic adenosine monophosphate, Cyclic adenosine monophosphate, Cyclic AMP

Additional Cyclic AMP Products

Product Documents for Cyclic AMP Antibody (9H4C4)

Certificate of Analysis

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Download SDS

Product Specific Notices for Cyclic AMP Antibody (9H4C4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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