Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones. The human Cyclophilin B precursor is 216 amino acids (aa) in length. It contains a 25 aa signal sequence plus a 191 aa mature region. There is a partial heparin-binding sequence (aa 27-34), a PPIase domain (aa 47-204) and a C-terminal ER retention motif (aa 213-216). Over aa 34-216, the human and mouse sequences are 95% aa identical.
Rat Cyclophilin B ELISA Kit (Colorimetric)
Novus Biologicals | Catalog # NBP3-06847
Key Product Details
Sample Type & Volume Required Per Well
Sensitivity
Assay Range
Product Specifications
Assay Type
Kit Type
Species
Specificity
Precision
Intra-Assay Precision (Precision within an assay) 5.33
Inter-Assay Precision (Precision between assays) 5.16
Recovery for Rat Cyclophilin B ELISA Kit (Colorimetric)
Recovery
Linearity
Scientific Data Images for Rat Cyclophilin B ELISA Kit (Colorimetric)
ELISA: Rat Cyclophilin B ELISA Kit (Colorimetric) [NBP3-06847] -
ELISA: Rat Cyclophilin B ELISA Kit (Colorimetric) [NBP3-06847] - Standard Curve ReferenceKit Contents for Rat Cyclophilin B ELISA Kit (Colorimetric)
- Biotinylated Detection Ab Diluent
- Concentrated Biotinylated Detection Ab (100x)
- Concentrated HRP Conjugate (100x)
- Concentrated Wash Buffer (25x)
- HRP Conjugate Diluent
- Micro ELISA Plate (Dismountable)
- Plate Sealer
- Product Manual
- Reference Standard
- Sample Diluent
- Stop Solution
- Substrate Reagent
Preparation and Storage
Shipping
Stability & Storage
Background: Cyclophilin B
Alternate Names
Gene Symbol
Additional Cyclophilin B Products
Product Documents for Rat Cyclophilin B ELISA Kit (Colorimetric)
Certificate of Analysis
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Product Specific Notices for Rat Cyclophilin B ELISA Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
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