Potent sphingosine-1-phosphate receptor 4 (S1P4
) agonist (EC50
= 45 nM). Displays no activity at other S1P receptor subtypes (S1P1-3
) at concentrations up to 25 μ
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists.
Guerrero et al.