hh CYM 50260 (CAS 1355026-60-6): R&D Systems
Catalog Number: 4677
Chemical Name: 2-Chloro-3-[2-(2,4-dichlorophenoxy)ethoxy]-6-(fluoromethyl)pyridine
Biological Activity
Potent sphingosine-1-phosphate receptor 4 (S1P4) agonist (EC50 = 45 nM). Displays no activity at other S1P receptor subtypes (S1P1-3 and S1P5) at concentrations up to 25 μM.
Technical Data
  • M.Wt:
    350.6
  • Formula:
    C14H11Cl3FNO2
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    1355026-60-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P4-R) agonists.
    Guerrero et al.
    Bioorg.Med.Chem.Lett., 2011;22:537

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