Chemical Name: 1-[2-[2,5-Dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-1,6-dihydro-6-oxo-3-pyridinecarbonitrile
Biological ActivityCYM 5520 is a selective S1P2 allosteric agonist (EC50 = 0.48 μM). Selective for S1P2 receptors over a panel of 29 other receptors and transporters.
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A sphingosine 1-phosphate receptor 2 selective allosteric agonist.
Satsu et al.
Citation for CYM 5520
The citations listed below are publications that use Tocris products. Selected citations for CYM 5520 include:
1 Citation: Showing 1 - 1
Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2.
Authors: Matsushima-Nishiwaki Et al.
PLoS One 2018;13:e0209050
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