Activator of small conductance Ca2+
channels that displays selectivity for KCa
2.2 (SK2) and KCa
2.3 (SK3) channels (EC50
values are 5.6 and 14 μ
M for KCa
2.3 and KCa
2.2 respectively). Displays no activity at KCa
2.1 (SK1) and KCa
3.1 (IK) channels.
Store at +4°C
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Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels.
Hougaard et al.
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