CyPPA

  ( 2 citations )    
Product Datasheet
Catalog Number:2953
Chemical Name:N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine
Product Details
Citations (2)
Reviews
Biological Activity
Activator of small conductance Ca2+-activated K+ channels that displays selectivity for KCa2.2 (SK2) and KCa2.3 (SK3) channels (EC50 values are 5.6 and 14 μM for KCa2.3 and KCa2.2 respectively). Displays no activity at KCa2.1 (SK1) and KCa3.1 (IK) channels.
Technical Data
  • M.Wt:
    285.39
  • Formula:
    C16H23N5
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    73029-73-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for CyPPA include:

2 Citations: Showing 1 - 2
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  1. Knockdown of the small conductance Ca(2+) -activated K(+) channels is potently cytotoxic in breast cancer cell lines.
    Authors: Abdulkareem Et al.
    J Exp Clin Cancer Res  2016;173:177
  2. Iberiotoxin-sensitive and -insensitive BK currents in Purkinje neuron somata.
    Authors: Benton Et al.
    J Neurophysiol  2013;109:2528

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