10 results for "Ca2+-Activated Potassium Channel Activators" in Products
Ca2+-Activated Potassium Channel Activators
There are 8 members of the KCa channel family, all of which are homo or heterotetramers of α-subunits, with either 6 or 7 transmembrane domains. Some family members also have associated regulatory subunits. KCa1.1 (BK), KCa2.x (SK) and KCa3.1 (IK) ion channels open in response to intracellular Ca2+ levels. Other KCa family members, KCa4.1, KCa4.2 (now known as KNa1.1 and KNa1.2) and KCa5.1 are grouped with KCa1.1 (BK) based on their structural similarities, however relatively little is ...
KCa1.1 (BK) channel activator
| Chemical Name: | 1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one |
| Purity: | ≥98% |
KCa1.1 (BK) channel activator
| Chemical Name: | N'-[3,5-Bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl-phenyl]thiourea |
| Purity: | ≥98% |
Activates Cl- conductance and hKCa3.1 channels
| Chemical Name: | 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one |
| Purity: | ≥99% |
Potent KCa1.1 (BK) channel opener
| Chemical Name: | 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one |
| Purity: | ≥98% |
KCa3.1 (IK) and KCa2 (SK) channel activator
| Chemical Name: | Naphtho[1,2-d]thiazol-2-ylamine |
| Purity: | ≥99% |
Positive modulator of KCa2 (SK) and KCa3.1 (IK) channels
| Chemical Name: | 6,7-Dichloro-1H-indole-2,3-dione 3-oxime |
| Purity: | ≥98% |
Selective KCa2.1 (SK) channel activator
| Chemical Name: | 4-[[[[(2-Methoxyphenyl)amino]carbonyl]oxy]methyl]-piperidinecarboxylic acid-1,1-dimethylethyl ester |
| Purity: | ≥99% |
KCa1.1 (BK) channel activator
| Chemical Name: | 5-[(4-Bromophenyl)methyl]-2-thiazolamine |
| Purity: | ≥99% |
KCa2.2 and KCa2.3 (SK) channel activator
| Chemical Name: | N-Cyclohexyl-N-[2-(3,5-dimethyl-pyrazol-1-yl)-6-methyl-4-pyrimidinamine |
| Purity: | ≥99% |
KCa1.1 (BK) channel activator
| Chemical Name: | Sodium 1-Amino-9,10-dioxo-4-((5,6,7,8-tetrahydronaphthalen-2-yl)amino)-9,10-dihydroanthracene-2-sulfonate |
| Purity: | ≥98% |