Chemical Name: (3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione
Biological ActivityInhibitor of actin polymerization. Inhibits cell division, migration and glucose transport. Causes G2/M cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma cells. Cell permeable.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Cytochalasin B may shorten actin filaments by a mechanism independent of barbed end capping.
Theodoropoulos et al.
Compartmentalization of transport and phosphorylation of glucose in a hepatoma cell line.
Whitesell et al.
Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment.
Buldak et al.
Citations for Cytochalasin B
The citations listed below are publications that use Tocris products. Selected citations for Cytochalasin B include:
2 Citations: Showing 1 - 2
Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia.
Authors: Bernier Et al.
Cell Rep 2019;27:2895
Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake.
Authors: Diaz-Garcia Et al.
Cell Metab 2017;26:361
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