Chemical Name: (3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione
Biological ActivityInhibitor of actin polymerization. Inhibits cell division, migration and glucose transport. Causes G2/M cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma cells. Cell permeable.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Cytochalasin B may shorten actin filaments by a mechanism independent of barbed end capping.
Theodoropoulos et al.
Compartmentalization of transport and phosphorylation of glucose in a hepatoma cell line.
Whitesell et al.
Changes in subcellular localization of visfatin in human colorectal HCT-116 carcinoma cell line after cytochalasin B treatment.
Buldak et al.
Citation for Cytochalasin B
The citations listed below are publications that use Tocris products. Selected citations for Cytochalasin B include:
1 Citation: Showing 1 - 1
Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake.
Authors: Diaz-Garcia Et al.
Cell Metab 2017;26:361
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