(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin

Tocris Bioscience | Catalog # 3377

Selective vasopressin V1A antagonist
Tocris Bioscience

Key Product Details

Description

Selective vasopressin V1A antagonist
View all Vasopressin Receptor Antagonists »

Product Description

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin is a selective vasopressin V1A receptor antagonist. Inhibits vasopressin and oxytocin-induced increases in intracellular calcium concentrations in vitro (IC50 values are 5 and 30 nM respectively). Exhibits potent and prolonged antivasopressor activity and induces anxiolytic-like effects in the dorsal, but not ventral, hippocampus in vivo.

Product Specifications

Molecular Weight

1151.38

Formula

C52H74N14O12S2

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

73168-24-8

PubChem ID

122173055

InChI Key

QVQOGNOOAMQKCE-LOVRMFBOSA-N

SMILES

COC1=CC=C(C[C@@H]2NC(=O)CC3(CCCCC3)SSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC3=CC=CC=C3)NC2=O)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 2mg/ml in water

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Product Documents

Certificate of Analysis

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Product Specific Notices

For research use only

Citations for (d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin

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