DAB2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-30488

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all DAB2 Primary Antibodies »

Product Specifications

Immunogen

Between 275 and 325

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit DAB2 Antibody - BSA Free (NBP3-30488) is a polyclonal antibody validated for use in WB and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for DAB2 Antibody - BSA Free

DAB2 Antibody

Immunoprecipitation:DAB2 AntibodyNBP3-30488] -

Immunoprecipitation:DAB2 AntibodyNBP3-30488] -Detection of human Dab2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-Dab2 antibody NBP3-30488 (lot NBP3-30488-1) used for IP at 6 µg/mg lysate. Dab2 was also immunoprecipitated by rabbit anti-Dab2 antibody for blotting immunoprecipitated Dab2, NBP3-30488 was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

Applications for DAB2 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DAB2

Disabled-2 (Dab2) is a component of the CSF-1 signal transduction pathway. Dab2 is involved in the regulation of cytoskeleton based functions by regulating cell positioning, inducing marcrophage adhesion, or regulation of protein trafficking of endocytosis involved proteins (1,2). Dab2 has been implicated in regulating the homeostasis of epithelial differentiation, where Dab2 is involved in endodermal cell formation, differentiation, and organization. Dab2 mRNA expression is common in normal ovarian epithelia cells but low or lack of expression is seen in ovarian carcinoma cell lines (3).

Long Name

Disabled Homolog 2, Mitogen-Responsive Phosphoprotein

Alternate Names

Disabled-2, DOC2

Gene Symbol

DAB2

Additional DAB2 Products

Product Documents for DAB2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for DAB2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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