Daunorubicin hydrochloride

Catalog # Availability Size / Price Qty
1467/10
Daunorubicin hydrochloride | CAS No. 23541-50-6 | Antibiotics
1 Image
Description: DNA topoisomerase II inhibitor
Alternative Names: Daunomycin

Chemical Name: (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyransoyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride

Purity: ≥98%

Product Details
Citations (3)
Reviews (1)

Biological Activity

Daunorubicin hydrochloride is a DNA topoisomerase II inhibitor. Inhibits RNA and DNA synthesis and causes DNA fragmentation in vivo. Reduces tau mRNA levels in vitro.Anticancer agent. Exhibits activity against nonlymphocytic leukemia. Identified as targeting human host proteins that interact with SARS-CoV-2. Also enhances adeno-associated virus transduction of HeLa cells in vitro.

Technical Data

M.Wt:
563.99
Formula:
C27H29NO10.HCl
Solubility:
Soluble to 50 mM in water
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
23541-50-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

⚠ WARNING: This product can expose you to chemicals including Daunorubicin hydrochloride, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Citations for Daunorubicin hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Daunorubicin hydrochloride include:

3 Citations: Showing 1 - 3

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Daunorubicin hydrochloride

Average Rating: 5 (Based on 1 Review)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used Daunorubicin hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Mechanism of action of Daunorubicin hydrochloride was studied
By Anonymous on 12/26/2019
Application: Species: Human

Mechanism of action of Daunorubicin hydrochloride was studied in order to understand the inhibition of the progression of the enzyme topoisomerase II, which relaxes supercoils in DNA for transcription.


Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.