DBM 1285 dihydrochloride

Catalog # Availability Size / Price Qty
5095/10
5095/50
DBM 1285 dihydrochloride | p38 Inhibitors
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Description: p38 MAPK inhibitor; anti-inflammatory

Chemical Name: N-Cyclopropyl-4-[4-(4-fluorophenyl)-2-(4-piperidinyl)-5-thiazolyl]-2-pyrimidinamine dihydrochloride

Purity: ≥98%

Product Details
Reviews

Biological Activity

p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF-α production in macrophages and in vivo. Attenuates zymosan-induced inflammation and adjuvant-induced arthritis in murine models. Orally active.

Technical Data

M.Wt:
468.42
Formula:
C21H22FN5S.2HCl
Solubility:
Soluble to 100 mM in water
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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