DCEBIO

Key Product Details

Product Description

DCEBIO is a stimulates Cl^- secretion via the activation of hK_Ca3.1 (IK1) potassium channels and an apical Cl^- conductance carried by the CFTR channel. More potent than its analog 1-EBIO (Cat. No. 1041).

Product Specifications for DCEBIO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for DCEBIO

The following data is based on the product molecular weight 231.08.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.33 mL	21.64 mL	43.28 mL
5 mM	0.87 mL	4.33 mL	8.66 mL
10 mM	0.43 mL	2.16 mL	4.33 mL
50 mM	0.09 mL	0.43 mL	0.87 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 29 publications citing the usage of this product.

• Hamilton and Kiessling DCEBIO stimulates Cl- secretion in the mouse jejunum. Am.J.Physiol.Cell Physiol. 2006 PMID: 16135545
• Singh Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease. J.Pharmacol.Exp.Ther. 2001 PMID: 11160649

Product Documents for DCEBIO