secretion via the activation of hKCa
3.1 (IK1) potassium channels and an apical Cl-
conductance carried by the CFTR channel. More potent than its analog 1-EBIO
(Cat. No. 1041).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
DCEBIO stimulates Cl- secretion in the mouse jejunum.
Hamilton and Kiessling et al.
Am.J.Physiol.Cell Physiol., 2006;290:152
Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease.
Singh et al.
The citations listed below are publications that use Tocris products. Selected citations for DCEBIO include:
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