DCEBIO

  ( 4 citations )    
Product Datasheet
Catalog Number:1422
Chemical Name:5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one
Product Details
Citations (4)
Reviews
Biological Activity
Stimulates Cl- secretion via the activation of hKCa3.1 (IK1) potassium channels and an apical Cl- conductance carried by the CFTR channel. More potent than its analog 1-EBIO (Cat. No. 1041).
Technical Data
  • M.Wt:
    231.08
  • Formula:
    C9H8Cl2N2O
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    60563-36-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for DCEBIO include:

4 Citations: Showing 1 - 4
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  1. Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells.
    Authors: McCully Et al.
    J Immunol  2015;195:96
  2. Benzimidazolones enhance the function of epithelial Na+ transport.
    Authors: Laube Et al.
    Br J Pharmacol  2013;168:1329
  3. Loss of Ca-mediated ion transport during colitis correlates with reduced ion transport responses to a Ca-activated K channel opener.
    Authors: Hirota and McKay
    Br J Pharmacol  2009;156:1085
  4. Chloride transporting capability of Calu-3 epithelia following persistent knockdown of the cystic fibrosis transmembrane conductance regulator, CFTR.
    Authors: MacVinish Et al.
    J Reprod Dev  2007;150:1055

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