Activator of epithelial KCa
channels, stimulates a large and sustained trans-epithelial Cl-
secretory response across T84 monolayers. Induces hyperpolarization to the same magnitude as ACh in aortic value endothelial cells. Promotes embryonic stem cell (ESC) differentiation into cardiomyocytes.
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1-Ethyl-2-benzimidazolinone stimulates endothelial KCa channels and nitric oxide formation in rat mesenteric vessels.
Ayotunde and Adeagbo
Modulation of Cl- secretion by benzimidazolones. I. Direct activation of a Ca2+ - dependent K+ channel.
Devor et al.
Reduced hyperpolarisation in endothelial cells of rabbit aortic value following chronic nitroglycerine administration.
Kusama et al.
Modulation of calcium-activated potassium channels induces cardiogenesis of pluripotent stem cells and enrichment of pacemaker-like cells.
Kleger et al.
The citations listed below are publications that use Tocris products. Selected citations for 1-EBIO include:
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