Desmocollin-2 Antibody (rDSC2/3437)

Novus Biologicals | Catalog # NBP3-49085

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 kappa Clone # rDSC2/3437 expressed in CHO
View all Desmocollin-2 Primary Antibodies »

Product Specifications

Immunogen

Recombinant full-length human DSC2 protein (Uniprot: Q02487)

Localization

Cell junction, Cell membrane, Desmosome

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Scientific Data Images for Desmocollin-2 Antibody (rDSC2/3437)

Desmocollin-2 Antibody (rDSC2/3437)

Western Blot: Desmocollin-2 Antibody (rDSC2/3437) [NBP3-49085] -

Western blot analysis of Human Intestine lysate using Desmocollin-2 Antibody (rDSC2/3437).

Applications for Desmocollin-2 Antibody (rDSC2/3437)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Desmocollin-2

Desmocollin 2 is encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms.

Alternate Names

ARVD11, CDHF2, Desmocollin2, DG2, DSC2

Gene Symbol

DSC2

Additional Desmocollin-2 Products

Product Documents for Desmocollin-2 Antibody (rDSC2/3437)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Desmocollin-2 Antibody (rDSC2/3437)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cadherin Superfamily

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FAQs

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