Recombinant Human Destrin His Protein

Name: Recombinant Human Destrin His Protein
Brand: Novus Biologicals
SKU: NBP1-98933
Price: 929 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-98933

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all Destrin Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 1-165 of Human Destrin

Source: E.coli

Amino Acid Sequence: MASGVQVADE VCRIFYDMKV RKCSTPEEIK KRKKAVIFCL SADKKCIIVE EGKEILVGDV GVTITDPFKH FVGMLPEKDC RYALYDASFE TKESRKEELM FFLWAPELAP LKSKMIYASS KDAIKKKFQG IKHECQANGP EDLNRACIAE KLGGSLIVAF EGCPVLEHHH HHH

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

19.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Destrin His Protein

SDS-PAGE: Recombinant Human Destrin His Protein [NBP1-98933]

SDS-Page: Recombinant Human Destrin Protein [NBP1-98933] - 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-98933

Formulation	20 mM Tris-HCl buffer (pH 8.0), 0.1 M NaCl, 10% glycerol, 1 mM DTT
Preservative	No Preservative
Concentration	0.5 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Destrin

Destrin (actin depolymerizing factor), also known as DSTN, is a member of the ADF/Cofilin/destrin superfamily that has the ability to rapidly depolymerize F-Actin in a stoichiometric manner. DSTN is a small phosphoinositide-sensitive actin-binding protein capable of depolymerizing actin-filaments in vitro. It is found in various epithelial and endothelial cells but is practically absent from adult mouse heart and skeletal muscle cells. DSTN shares 71% sequence homology with Cofilin, however the two proteins differ in their interaction with Actin. Recombinant human DSTN protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

ACTDPdestrin, Actin-depolymerizing factor, ADFbA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP)), bA462D18.2, destrin (actin depolymerizing factor), DSN

Gene Symbol

DSTN

Additional Destrin Products

Product Documents for Recombinant Human Destrin His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human Destrin His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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