Indirectly agonizes serotonin receptors via inhibition of 5-HT re-uptake and stimulation of 5-HT release. Anorectic agent; decreases growth hormone, insulin, leptin, fat mass, lean mass and increases ghrelin in diet-switched diet-induced obese mice.
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Neuropharmacological effects of low and high doses of repeated oral dexfenfluramine in rats: a comparison with fluoxetine.
Caccia et al.
Influence of the 5-HT2C receptor antagonist SB242,084 on behaviour produced by the 5-HT2 agonist Ro60-0175 and the indirect 5-HT agonist dexfenfluramine.
Higgins et al.
Chronic treatment with either dexfenfluramine or sibutramine in diet-switched diet-induced obese mice.
Bush et al.
The citations listed below are publications that use Tocris products. Selected citations for Dexfenfluramine hydrochloride include:
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