Dexfenfluramine hydrochloride

Key Product Details

Product Description

Indirectly agonizes serotonin receptors via inhibition of 5-HT re-uptake and stimulation of 5-HT release. Anorectic agent; decreases growth hormone, insulin, leptin, fat mass, lean mass and increases ghrelin in diet-switched diet-induced obese mice.

Product Specifications for Dexfenfluramine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Dexfenfluramine hydrochloride

The following data is based on the product molecular weight 267.72.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.74 mL	18.68 mL	37.35 mL
5 mM	0.75 mL	3.74 mL	7.47 mL
10 mM	0.37 mL	1.87 mL	3.74 mL
50 mM	0.07 mL	0.37 mL	0.75 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

• Higgins Influence of the 5-HT_2C receptor antagonist SB242,084 on behaviour produced by the 5-HT₂ agonist Ro60-0175 and the indirect 5-HT agonist dexfenfluramine. Br.J.Pharmacol. 2001 PMID: 11399662
• Bush Chronic treatment with either dexfenfluramine or sibutr. in diet-switched diet-induced obese mice. Endocrine 2006 PMID: 16785615
• Caccia Neuropharmacological effects of low and high doses of repeated oral dexfenfluramine in rats: a comparison with fluox. Pharmacol.Biochem.Behav. 1997 PMID: 9259015

Product Documents for Dexfenfluramine hydrochloride