Dibutyryl-cAMP, sodium salt

Tocris Bioscience | Catalog # TB1141-RMU

Dibutyryl-cAMP, sodium salt synthesized to Ancillary Material Grade
Tocris Bioscience

Key Product Details

Description

Dibutyryl-cAMP, sodium salt synthesized to Ancillary Material Grade

Alternative Names

Bucladesine sodium
View all Ancillary Material Grade Compounds »

Product Description

Dibutyryl-cAMP sodium salt is a cell-permeable analog of cAMP that activates cAMP-dependent protein kinases and is a phosphodiesterase inhibitor. Combined with other reagents, dibutyryl-cAMP promotes differentiation of neural stem/progenitor cells (NSPCs) and other cell lines (see our protocol below) and increases survival rates of NSPCs and differentiation into neurons in vivo. Promotes neurite outgrowth in cell cultures. Dibutyryl-cAMP has anti-inflammatory activity and is used to promote wound healing. Choline acetyltransferase and vesicular acetylcholine transporter mRNA are increased in cells treated with dibutyryl-cAMP.

For more information about how Dibutyryl-cAMP, sodium salt may be used, see our protocol: Generating Midbrain Dopaminergic Neurons from hPSCs

This product is Bio-Techne's ancillary Material Grade version of Dibutyryl-cAMP sodium salt (Cat. No. 1141). Suitable for use in research and further manufacturing of cell therapies. Find out more about our Ancillary Material Grade product range.

Product Specifications for Dibutyryl-cAMP, sodium salt

Molecular Weight

491.37

Formula

C18H23N5NaO8P

Storage

Store at -20°C (± 5°C)

Purity

≥98%

Chemical Name

N6,O2'-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt

CAS Number

16980-89-5

PubChem ID

23663967

InChI Key

KRBZRVBLIUDQNG-JBVYASIDSA-M

SMILES

[H][C@]([C@]1([H])[C@H]2OC(CCC)=O)(COP(O1)([O-])=O)O[C@H]2N3C=NC4=C3N=CN=C4NC(CCC)=O.[Na+]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

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Product Documents for Dibutyryl-cAMP, sodium salt

Certificate of Analysis

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Product Specific Notices for Dibutyryl-cAMP, sodium salt

For research use only

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