Dihydrexidine hydrochloride

Catalog # Availability Size / Price Qty
0884/25
0884/5
Dihydrexidine hydrochloride | CAS No. 158704-02-0 | Dopamine D1 and D5 Receptor Agonists
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Description: Selective D1-like agonist

Chemical Name: (±)-trans-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine hydrochloride

Purity: ≥98%

Product Details
Citations (4)
Supplemental Products
Reviews (1)

Biological Activity

A potent, full efficacy dopamine D1 agonist which shows no agonist activity at peripheral D2 receptors or adrenoceptors at doses which cause maximal stimulation of D1 sites. The compound appears to be fully bioavailable in brain and exhibits profound antiparkinsonism effects in vivo.

Technical Data

M.Wt:
303.79
Formula:
C17H17NO2.HCl
Solubility:
Soluble to 10 mM in water and to 50 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
158704-02-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license, US Patent 5,047,536

Product Datasheets

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Citations for Dihydrexidine hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Dihydrexidine hydrochloride include:

4 Citations: Showing 1 - 4

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Reviews for Dihydrexidine hydrochloride

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Dose Response of Tango D1-bla Dopamine Receptor Signaling
By Anonymous on 08/20/2018
Application: Species: Human

I used this as our positive control when testing dose responses following treatment with our Tango D1-bla U20S cells to measure dopamine receptor 1 activity following treatment with Dihydrexidine.


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