Disulfiram

  ( 2 citations )    
Product Datasheet
Catalog Number:3807
Alternate Names:Tetraethylthiuram disulfide
Chemical Name:Bis(diethylthiocarbamyoyl)disulfide
Product Details
Citations (2)
Reviews
Biological Activity
Inhibitor of aldehyde dehydrogenase that displays antialcoholism activity. Shown to reversibly stimulate Ca2+-ATPase activity and inhibit V-ATPase (EC50 = 26 μM). Also inhibits expression of MMP-2 and MMP-9 and displays anti-invasive activity.
Technical Data
  • M.Wt:
    296.54
  • Formula:
    C10H20N2S4
  • Solubility:
    Soluble to 20 mM in DMSO and to 100 mM in ethanol
  • Storage:
    Store at +4°C
  • CAS No:
    97-77-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Disulfiram include:

2 Citations: Showing 1 - 2
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  1. Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring.
    Authors: Ahadome Et al.
    JCI Insight  2016;1:e87001
  2. HIV-1 latency and virus production from unintegrated genomes following direct infection of resting CD4 T cells.
    Authors: Chan Et al.
    PLoS One  2016;13:1

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