DLL4 Antibody

Novus Biologicals | Catalog # NBP2-27407

Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
View all DLL4 Primary Antibodies »

Product Specifications

Immunogen

Partial synthetic peptide between amino acids 550-610 of human DLL4.

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in human and 94% homologous in mouse.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DLL4 Antibody

Western Blot: DLL4 Antibody [NBP2-27407]

Western Blot: DLL4 Antibody [NBP2-27407]

Western Blot: DLL4 Antibody [NBP2-27407] - Analysis of DLL4 in HUVEC cell lysate using 1) preimmune sera at 1:5000 and 2) NBP2-27407 at 3 ug/ml, and 3) mouse embryo body lysate at 6 ug/ml. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.

Applications for DLL4 Antibody

Application
Recommended Usage

Western Blot

3-6ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DLL4

Delta-like protein 4 is a single pass type 1 transmembrane protein which plays an important role in the Notch signaling pathway by activating Notch-1 and Notch-4. DLL-4 contains a signal sequence, a DSL domain, eight epidermal growth factor-like repeats, a transmembrane domain, and an intracellular region, all of which are characteristics of members of the Delta protein family. It is essential for angiogenesis during embryonic vascular development and is involved in tumour angiogenesis.

Long Name

Delta-like 4

Alternate Names

delta 4, Delta 4 precursor, delta ligand 4, delta4, delta-like 4 (Drosophila), delta-like 4 homolog, delta-like 4 homolog (Drosophila), delta-like 4 protein, delta-like protein 4, Drosophila Delta homolog 4, hdelta2, MGC126344, notch ligand delta-2, notch ligand DLL4

Gene Symbol

DLL4

UniProt

Q9NR61

Additional DLL4 Products

Product Documents for DLL4 Antibody

Certificate of Analysis

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Product Specific Notices for DLL4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Stem Cell Markers
Notch Pathway

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FAQs

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Associated Pathways

Notch Signaling Pathways Notch Signaling Pathway Thumbnail