DMBT1/GP340 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-38471

Novus Biologicals
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all DMBT1 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: STPAPFLNITRPNTDYSCGGFLSQPSGDFSSPFYPGNYPNNAKCVWDIEVQNNYRVTVIFRDVQLEGGCNYDYIEVFDGPYRSSPLIARVCDGAR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DMBT1/GP340 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: DMBT1/GP340 Antibody [NBP2-38471]

Immunocytochemistry/ Immunofluorescence: DMBT1/GP340 Antibody [NBP2-38471]

Immunocytochemistry/Immunofluorescence: DMBT1/GP340 Antibody [NBP2-38471] - Staining of human cell line RH-30 shows localization to microtubule organizing center. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471] - Analysis in human small intestine and pancreas tissues. Corresponding DMBT1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471] - Staining of human lung shows weak cytoplasmic positivity in macrophages.
Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471]

Immunohistochemistry-Paraffin: DMBT1/GP340 Antibody [NBP2-38471] - Staining of human prostate shows no positivity in glandular cells as expected.

Applications for DMBT1/GP340 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation/Permeabilization: PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: DMBT1

Glycoprotein-340 is member of the scavenger receptor superfamily and has been identified as a putative SP-D receptor. Gp-340 has been shown to bind SP-D in a calcium dependent manner through a protein-protein interaction. Like SP-D, gp-340 is mainly found in lung tissue and immunohistochemistry revealed high expression in alveolar macrophages (1). An identical protein is present in saliva (salivary agglutinin) and both forms are encoded by the gene DMBT1 (5).

Long Name

Deleted in Malignant Brain Tumors 1

Alternate Names

CRP-ductin, Ebnerin, GP340, Hensin, Muclin, SAG, Vomeroglandin

Gene Symbol

DMBT1

UniProt

Q9UGM3 (Human)

Additional DMBT1 Products

Product Documents for DMBT1/GP340 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for DMBT1/GP340 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers

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Protocols

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FAQs

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