DMOG

Tocris Bioscience | Catalog # 4408

Prolyl hydroxylase inhibitor
Tocris Bioscience

Key Product Details

Description

Prolyl hydroxylase inhibitor
View all Hydroxylase Inhibitors »

Product Description

DMOG is a prolyl 4-hydroxylase (P4H) inhibitor; inhibits hypoxia-inducible factor α (HIF-α) prolyl hydroxylase (HIF-PH). Increases levels of HIF-1α; promotes cell survival under hypoxic conditions. Inhibits differentiation of hematopoietic stem cells (HSCs) in culture.

Product Specifications for DMOG

Molecular Weight

175.14

Formula

C6H9NO5

Storage

Store at -20°C

Purity

≥97% (HPLC)

Chemical Name

N-(2-Methoxy-2-oxoacetyl)glycine methyl ester

CAS Number

89464-63-1

PubChem ID

560326

InChI Key

BNJOZDZCRHCODO-UHFFFAOYSA-N

SMILES

O=C(C(OC)=O)NCC(OC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 17.51 100
DMSO 17.51 100

Preparing Stock Solutions for DMOG

The following data is based on the product molecular weight 175.14.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.71 mL 28.55 mL 57.10 mL
5 mM 1.14 mL 5.71 mL 11.42 mL
10 mM 0.57 mL 2.85 mL 5.71 mL
50 mM 0.11 mL 0.57 mL 1.14 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Product Documents for DMOG

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DMOG

For research use only

Related Research Areas

Redox Enzymes

Customer Reviews for DMOG (2)

5 out of 5
2 Customer Ratings
5 Stars
100%
4 Stars
0%
3 Stars
0%
2 Stars
0%
1 Stars
0%

Have you used DMOG?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Customer Images

Showing  1 - 2 of 2 reviews Showing All
Filter By:
Clear Filters X
  • DMOG
    Name: shubham dubey
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: A549
    Verified Customer | Posted 12/22/2021
    IN cell culture to stabilize HIF1
    DMOG 4408
  • Good product
    Name: P Kumar
    Species: Human
    Assay Type: In Vitro
    Cell Line/Tissue: A549
    Verified Customer | Posted 05/27/2021
    To check the HIF2a activity in A549 cells.
    DMOG 4408

There are no reviews that match your criteria.

Showing  1 - 2 of 2 reviews Showing All