DPDPE

  ( 9 citations )    
Product Datasheet
Catalog Number:1431
Alternate Names:[D-Pen2,5]Enkephalin, [D-Pen2,D-Pen5]Enkephalin
Chemical Name:
Product Details
Citations (9)
Supplemental Products
Reviews
Biological Activity
Prototypical selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.
Technical Data
  • M.Wt:
    645.79
  • Formula:
    C30H39N5O7S2
  • Sequence:
    YXGFX

    (Modifications: X = D-Pen, Disulfide bridge between 2 - 5)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    88373-73-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for DPDPE include:

9 Citations: Showing 1 - 9
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  1. Multisite tyrosine phosphorylation of the N-terminus of Mint1/X11α by Src kinase regulates the trafficking of amyloid precursor protein.
    Authors: Dunning Et al.
    J Neurochem  2016;137:518
  2. Inhibition of Anopheles gambiae odorant receptor function by mosquito repellents.
    Authors: Tsitoura Et al.
    J Biol Chem  2015;290:7961
  3. Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects.
    Authors: Largent-Milnes Et al.
    J Pharmacol Exp Ther  2013;347:7
  4. Peripheral δ-opioid receptors attenuate the exercise pressor reflex.
    Authors: Leal Et al.
    PLoS One  2013;305:H1246
  5. Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111.
    Authors: Marti Et al.
    Br J Pharmacol  2013;168:863
  6. Ligand-directed functional selectivity at the mu opioid receptor revealed by label-free integrative pharmacology on-target.
    Authors: Morse Et al.
    PLoS One  2011;6:e25643
  7. Activation of peripheral δ-opioid receptors leads to anti-hyperalgesic responses in the masseter muscle of male and female rats.
    Authors: Saloman Et al.
    Am J Physiol Heart Circ Physiol  2011;190:379
  8. Sex differences in the contribution of ATP-sensitive K+ channels in trigeminal ganglia under an acute muscle pain condition.
    Authors: Niu Et al.
    Neuroscience  2011;180:344
  9. Impaired p38 MAPK/HSP27 signaling underlies aging-related failure in opioid-mediated cardioprotection.
    Authors: Peart Et al.
    J Mol Cell Cardiol  2007;42:972

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