DQP 1105

  ( 1 citations )    
Product Datasheet
Catalog Number:4491
Chemical Name:5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid
Product Details
Citations (1)
Biological Activity
Noncompetitive NMDA receptor antagonist; displays over 50-fold selectivity for GluN2D- and GluN2C-containing receptors over GluN2B-, GluK2-, GluA1- and GluN2A-containing receptors (IC50 values are 2.7, 8.5, 121, 153, 198 and 206 μM, respectively). Reduces frequency of channel opening.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets

The citations listed below are publications that use Tocris products. Selected citations for DQP 1105 include:

1 Citations: Showing 1 - 1

  1. Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model.
    Authors: Lozovaya Et al.
    Nat Commun  2014;5:4563


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