DR3/TNFRSF25 Antibody Blocking Peptide

Name: DR3/TNFRSF25 Antibody Blocking Peptide
Brand: Novus Biologicals
SKU: NBP1-77019PEP
Price: 169 USD
Availability: InStock

Novus Biologicals | Catalog # NBP1-77019PEP

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Product Specifications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

Synthetic

Applications

Antibody Competition

View all DR3/TNFRSF25 Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 19 amino acids near the extracellular domain of human DR3.

Source: Synthetic

(Accession #: AAQ88676)

Application Notes

This peptide is useful as a blocking peptide for NBP1-77019.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NBP1-77019PEP

Formulation	PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative	0.02% Sodium Azide
Concentration	0.2 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at -20C. Avoid freeze-thaw cycles.

Background: DR3/TNFRSF25

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family, through their death domain containing receptors TNFR1 and Fas. A cell surface receptor with a death domain, DR3, has been identified by several groups independently, although it has been given alternative names. The ligand for DR3 has very recently been identified as TWEAK, also termed Apo3L. DR3 is highly expressed in tissues enriched in lymphocytes including PBL, thymus and spleen. DR3 mediates activation of NF kappa B, and induces apoptosis. DR3 may also play a role in regulating lymphocyte homeostasis.

Long Name

Death Receptor 3

Alternate Names

Apo-3, LARD, TNFRSF25, TRAMP, WSL-1

Gene Symbol

TNFRSF25

Additional DR3/TNFRSF25 Products

Product Documents for DR3/TNFRSF25 Antibody Blocking Peptide

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Certificate of Analysis

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Product Specific Notices for DR3/TNFRSF25 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.