DREADD agonist 21 dihydrochloride

Tocris Bioscience | Catalog # 6422

Potent hM3Dq and hM4Di DREADD agonist; water soluble version of DREADD agonist 21 (Cat. No. 5548)
Tocris Bioscience

Key Product Details

Description

Potent hM3Dq and hM4Di DREADD agonist; water soluble version of DREADD agonist 21 (Cat. No. 5548)

Alternative Names

Compound 21 (water-soluble)
View all DREADD Activators »

Product Description

DREADD agonist 21 dihydrochloride is a water soluble version of DREADD agonist 21 (Cat. No. 5548). Potent muscarinic DREADD agonist.

Product Specifications for DREADD agonist 21 dihydrochloride

Molecular Weight

351.27

Formula

C17H18N4.2HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride

CAS Number

2250025-92-2

PubChem ID

134812837

InChI Key

SETCOPAXYQJWKI-UHFFFAOYSA-N

SMILES

C1(N2CCNCC2)=NC(C=CC=C3)=C3NC4=C1C=CC=C4.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 35.13 100
DMSO 35.13 100

Preparing Stock Solutions for DREADD agonist 21 dihydrochloride

The following data is based on the product molecular weight 351.27.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.85 mL 14.23 mL 28.47 mL
5 mM 0.57 mL 2.85 mL 5.69 mL
10 mM 0.28 mL 1.42 mL 2.85 mL
50 mM 0.06 mL 0.28 mL 0.57 mL

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 17 publications citing the usage of this product.

Product Documents for DREADD agonist 21 dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DREADD agonist 21 dihydrochloride

For research use only

Citations for DREADD agonist 21 dihydrochloride

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