DREADD agonist 21 dihydrochloride
Chemical Name: 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine dihydrochloride
Biological ActivityDREADD agonist 21 dihydrochloride is a water soluble version of DREADD agonist 21 (Cat. No. 5548). Potent muscarinic DREADD agonist.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
The first structure-activity relationship studies for designer receptors exclusively activated by designer drugs.
Chen et al.
ACS Chem.Neurosci., 2015;18:476
Citations for DREADD agonist 21 dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for DREADD agonist 21 dihydrochloride include:
5 Citations: Showing 1 - 5
Medial and dorsal lateral septum involving social disruption stress-primed escalation in acid-induced writhes.
Authors: Lung Et al.
Front Mol Neurosci 2023;16:1158525
Activation of basolateral amygdala to anterior cingulate cortex circuit alleviates MK-801 induced social and cognitive deficits of schizophrenia.
Authors: Xin Et al.
Front Cell Neurosci 2023;16:1070015
Neural activity in the mouse claustrum in a cross-modal sensory selection task.
Authors: Su-Jeong Et al.
Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation.
Authors: Nizar N Et al.
Cell Host Microbe 2020;27:614-628.e6
Estimation of Current and Future Physiological States in Insular Cortex.
Authors: Mark L Et al.
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