Positive allosteric modulator of δ
-subunit containing GABAA
= 142 nM for α
receptors). Displays no effects on GABA responses mediated by α
2 and α
Soluble to 50 mM in DMSO
Desiccate at +4°C
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Novel compounds selectively enhance δ subunit containing GABAA receptors and increase tonic currents in thalamus.
Wafford et al.
The citations listed below are publications that use Tocris products. Selected citations for DS2 include:
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