DTX1 Antibody

Novus Biologicals | Catalog # NBP1-46126

Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Canine

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all DTX1 Primary Antibodies »

Product Specifications

Immunogen

Peptide with sequence CHHIENVLKEDAR corresponding to internal region (near N-Terminus) according to NP_004407.2.

Epitope

internal region (near N Terminus)

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Description

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Applications for DTX1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000
Application Notes
WB: Preliminary experiments gave an approx. 48 kDa band in mouse Fetal brain lysates and in lysates of NIH3T3 after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 67.4 kDa band according to human NP_004407.2 and of 68.2 kDa band according to mouse NP_032078.2. The 48 kDa band was successfully blocked by incubation with the immunizing peptide.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DTX1

DTX1, also known as E3 ubiquitin-protein ligase DTX1, is a 67.4 kDa, 620 amino acid protein that is involved in regulating the Notch pathway by monitoring ubiquitination and stimulating the breakdown of MEKK1. Current research is being conducted with diseases and disorders such as osteosarcoma, Noonan syndrome, and neuronitis. The protein interacts in disease and Notch signaling pathways with CRK, ITCH, UBE2D2, UBE2D3, and UBC.

Long Name

Deltex 1

Alternate Names

Deltex1, Dx-1

Entrez Gene IDs

1840 (Human); 14357 (Mouse); 687424 (Rat)

Gene Symbol

DTX1

UniProt

NP_004407.2 (Human)

Additional DTX1 Products

Product Documents for DTX1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for DTX1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Notch Pathway

Customer Reviews for DTX1 Antibody

There are currently no reviews for this product. Be the first to review DTX1 Antibody and earn rewards!

Have you used DTX1 Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies