Catalog Number: 2266
Chemical Name: N-(4-(Diethylaminobenzylidenyl)-N'-(4-hydroxybenzoyl)-hydrazine
Biological Activity
Novel selective agonist at estrogen-related receptors ERRβ and ERRγ. Displays minimal activity at ERRα, ERα and ERβ at concentrations up to 30 μM.
Technical Data
  • M.Wt:
    311.38
  • Formula:
    C18H21N3O2
  • Solubility:
    Soluble to 10 mM in ethanol and to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    95167-41-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Identification of an agonist ligand for estrogen-related receptors ERRβ/γ.
    Yu and Forman
    Bioorg.Med.Chem.Lett., 2005;15:1311
Citations:

The citations listed below are publications that use Tocris products. Selected citations for DY131 include:

4 Citations: Showing 1 - 4
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  1. Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells.
    Authors: Lu Et al.
    Neuropharmacology 2015;16:21
  2. Estrogen-related receptor β deletion modulates whole-body energy balance via estrogen-related receptor γ and attenuates neuropeptide Y gene expression.
    Authors: Byerly Et al.
    Eur J Neurosci 2013;37:1033
  3. Estrogen-related receptor β deficiency alters body composition and response to restraint stress.
    Authors: Byerly Et al.
    BMC Physiol 2013;13:10
  4. Identification and characterization of estrogen receptor-related receptor alpha and gamma in human glioma and astrocytoma cells.
    Authors: Gandhari Et al.
    Mol Cell Endocrinol 2010;315:314

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