DYRK1A Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-28906

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all DYRK1A Primary Antibodies »

Product Specifications

Immunogen

Between 713 and 763

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DYRK1A Antibody - BSA Free

DYRK1A Antibody

Western Blot:[NBP3-28906]-

Western Blot:[NBP3-28906]-Detection of human DYRK1A by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa, HEK293T and Jurkat cells. Antibodies: Affinity purified rabbit antibody used for WB at 0. 1 µg/ml and 1 µg/ml and used for IP at 6 µg/mg lysate. DYRK1A was also immunoprecipitated by rabbit antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds and 10 seconds.
DYRK1A Antibody

Western Blot:[NBP3-28906]-

Western Blot:[NBP3-28906]-DYRK1A Antibody

Applications for DYRK1A Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Tris-citrate/phosphate buffer, pH 7 to 8

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: DYRK1A

DYRK1A encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms.

Long Name

Dual-specificity Tyrosine-[Y]-phosphorylation Regulated Kinase 1A

Alternate Names

MNBH

Gene Symbol

DYRK1A

Additional DYRK1A Products

Product Documents for DYRK1A Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for DYRK1A Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Intracellular Kinases
Notch Pathway

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FAQs

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Associated Pathways

Notch Signaling Pathways Notch Signaling Pathway Thumbnail