Chemical Name: 4-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl)-benzoic acid
Biological ActivityEC 23 is a photostable synthetic retinoid; analog of ATRA (Cat. No. 0695). Displays similar activity to ATRA when tested on the embryonal carcinoma stem cell model TERA2.cl.SP12. Potently induces neural differentiation in human pluripotent embryonic stem cells.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation.
Christie et al.
Synthetic retinoids: structure-activity relationships.
Barnard et al.
Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues: identification of major retinoid-inducible proteins.
Maltman et al.
Citation for EC 23
The citations listed below are publications that use Tocris products. Selected citations for EC 23 include:
1 Citation: Showing 1 - 1
Morpho-Rheological Fingerprinting of Rod Photoreceptors Using Real-Time Deformability Cytometry.
Authors: Santos-Ferreira Et al.
Cytometry A 2019;
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