eIF4A i28 New
Chemical Name: 2-(5-(4-Butylphenyl)furan-2-yl)-6-nitroquinoline-4-carboxylic acid
Biological ActivityeIF4A i28 is a eukaryotic initiation factor-4A (eIF4A) inhibitor (IC50 = 8.60 μM in an eIF4A ATPase assay). It decreases BJAB Burkitt lymphoma cell viability (EC50 = 0.46 μM in a CellTiter-Glo (CTG) luminescence cell viability assay. It acts as an RNA-competitive, ATP-uncompetitive eIF4A inhibitor.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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