Recombinant Human eIF4EBP2 His Protein

Novus Biologicals | Catalog # NBP1-51034

Novus Biologicals
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Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE
View all eIF4EBP2 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-120 of Human eIF4EBP2

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSSSAGSGHQ PSQSRAIPTR TVAISDAAQL PHDYCTTPGG TLFSTTPGGT RIIYDRKFLL DRRNSPMAQT PPCHLPNIPG VTSPGTLIED SKVEVNNLNN LNNHDRKHAV GDDAQFEMDI

Purity

>85%, by SDS-PAGE

Predicted Molecular Mass

15.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human eIF4EBP2 His Protein

SDS-PAGE: Recombinant Human eIF4EBP2 His Protein [NBP1-51034]

SDS-PAGE: Recombinant Human eIF4EBP2 His Protein [NBP1-51034]

SDS-Page: Recombinant Human eIF4EBP2 His Protein [NBP1-51034] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

Formulation, Preparation, and Storage

NBP1-51034
Formulation 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 1 mM DTT, 0.1 M NaCl
Preservative No Preservative
Concentration 0.5 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: eIF4EBP2

EIF4EBP2 is a member of the eukaryotic translation initiation factor 4E binding protein family. This protein binds eIF4E and inhibits translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. It mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. Regulation of this protein has been implicated in cell proliferation, cell differentiation and viral infection. Recombinant human EIF4EBP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Alternate Names

4EBP2, 4E-BP2, eIF4E-binding protein 2, eukaryotic translation initiation factor 4E binding protein 2, eukaryotic translation initiation factor 4E-binding protein 2, PHASII, phosphorylated, heat and acid stable regulated by insulin protein II

Gene Symbol

EIF4EBP2

Additional eIF4EBP2 Products

Product Documents for Recombinant Human eIF4EBP2 His Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human eIF4EBP2 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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