Eltoprazine hydrochloride

Catalog # Availability Size / Price Qty
1860/10
Eltoprazine hydrochloride | CAS No. 98206-09-8 | 5-HT1B Receptor Agonists
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Description: 5-HT1 and 5-HT2C partial agonist

Chemical Name: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride

Purity: ≥98%

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Biological Activity

5-HT1 and 5-HT2C receptor partial agonist (Ki values are 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively). Reduces 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo.

Technical Data

M.Wt:
256.73
Formula:
C12H16N2O2.HCl
Solubility:
Soluble to 100 mM in water
Purity:
≥98%
Storage:
Store at RT
CAS No:
98206-09-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Discriminative stimulus properties of eltoprazine.
    Gommans et al.
    Life Sci., 1997;61:11
  2. Brain 5-HT and inhibition of aggressive behavior in animals: 5-HIAA and receptor subtypes.
    Miczek et al.
    Psychopharmacol.Bull., 1989;25:399
  3. Neurochemical profile of eltoprazine.
    Schipper et al.
    Drug Metabol.Drug Interact., 1990;8:85

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