Catalog Number: 1860
Chemical Name: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-piperazine hydrochloride
Biological Activity
5-HT1 and 5-HT2C receptor partial agonist (Ki values are 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively). Reduces 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Discriminative stimulus properties of eltoprazine.
    Gommans et al.
    Life Sci., 1997;61:11
  2. Brain 5-HT and inhibition of aggressive behavior in animals: 5-HIAA and receptor subtypes.
    Miczek et al.
    Psychopharmacol.Bull., 1989;25:399
  3. Neurochemical profile of eltoprazine.
    Schipper et al.
    Drug Metabol.Drug Interact., 1990;8:85
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