Epiblastin A

Catalog # Availability Size / Price Qty
6340/25
6340/5
Casein Kinase 1 Inhibitors Small Molecule
1 Image
Description: CK1 inhibitor; converts epiblast stem cells to ESCs and promotes ESC self-renewal

Chemical Name: 6-(3-Chlorophenyl)-2,4,7-pteridinetriamine

Purity: ≥98%

Product Details
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Biological Activity

CK1 inhibitor (IC50 values are 0.8, 3.7 and 3.8 μM for CK1δ, CK1ε and CK1α). Converts late-stage epiblast stem cells into germline-competent embryonic SC-like cells. Promotes activation and maintenance of the pluripotency network. Promotes ESC self-renewal at a concentration of 2 μM.

Technical Data

M.Wt:
287.71
Formula:
C12H10CIN7
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
16470-02-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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