10 results for "Casein Kinase 1 Inhibitors" in Products
Casein Kinase 1 Inhibitors
Casein kinases are a group of ubiquitous Ser/Thr kinases that phosphorylate key regulatory proteins involved in the control of cell differentiation, proliferation, chromosome segregation, circadian rhythms, and metabolic pathways. CK1 family members share a highly conserved kinase domain but differ in their variable N- and C-terminal domains. The C...
CK1 inhibitor
| Chemical Name: | N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride |
| Purity: | ≥99% |
Selective CK1 inhibitor. Also inhibits TGF-βRI
| Chemical Name: | 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
| Purity: | ≥98% |
Potent and selective CK1ε and CK1δ inhibitor
| Chemical Name: | 4-[1-Cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine dihydrochloride |
| Purity: | ≥98% |
Potent CK1 inhibitor; also inhibits cyclin-dependent kinases
| Chemical Name: | 2-[[9-(1-Methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]-9H-purin-2-yl]amino]-1-butanol dihydrochloride |
| Purity: | ≥98% |
Selective casein kinase 1ε inhibitor
| Chemical Name: | 3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride |
| Purity: | ≥98% |
Cdk inhibitor; potently inhibits cdk1 and cdk2; also inhibits CK1; acts as molecular glue
| Chemical Name: | (2R)-2-[[9-(Methylethyl)-6-[[[4-(2-pyridinyl)phenyl]methyl]amino]-9H-purin-2-yl]amino]-1-butanol trihydrochloride |
| Purity: | ≥98% |
Potent and selective CK1α, CK1δ and CK1ε inhibitor
| Chemical Name: | 4-(1-((4-Fluoro-1-methylpiperidin-4-yl)methyl)-4-(5-fluoropyridin-2-yl)-1H-imidazol-5-yl)-1H-pyrrolo[2,3-b]pyridine |
| Purity: | ≥98% |
Potent CK1δ/ε inhibitor
| Chemical Name: | 4-[4-(4-Fluorophenyl)-1-[1-(3-isoxazolylmethyl)-4-piperidinyl]-1H-imidazol-5-yl]-2-pyrimidinamine |
| Purity: | ≥98% |
Potent p38 MAPK inhibitor; anti-inflammatory
| Chemical Name: | N-[4-[2-Ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide |
| Purity: | ≥98% |
Potent and selective CK1α molecular glue Degrader
| Chemical Name: | 3-(5-(Benzo[d]isoxazol-3-ylamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione |
| Purity: | ≥98% |
