agonist; displays >200-fold selectivity for ERβ
values are 5 and 1216 nM for human ERβ
; 3.1 and 620 nM for rat ERβ
; and 3.7 and 750 nM for mouse ERβ
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold for research purposes under agreement from Pfizer Inc.
Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligands.
Malamas et al.
Evaluaton of an estrogen receptor-β agonist in animal models of human disease.
Harris et al.
Selective estrogen receptor-γ agonists repress transcription of proinflammatory genes.
Cvoro et al.