Catalog Number: 4796
Chemical Name: (+)-(S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate
Biological Activity
Selective 5-HT reuptake inhibitor (Ki values are 0.89, 8150, and 10500 nM for serotonin, noradrenalin, and dopamine transporters respectively). Is a S-enantiomer and eutomer of citalopram (Cat. No. 1427).
Technical Data
  • M.Wt:
    414.43
  • Formula:
    C20H21FN2O.C2H2O4
  • Solubility:
    Soluble to 50 mM in water and to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at +4°C
  • CAS No:
    219861-08-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Structure-activity relationships for a novel series of citalopram (1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) analogues at monoamine transporters.
    Zhang et al.
    J.Med.Chem., 2010;53:6112
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Escitalopram oxalate include:

1 Citations: Showing 1 - 1

  1. Generation of serotonin neurons from human pluripotent stem cells.
    Authors: Lu Et al.
    J Exp Med 2016;34:89

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