Etomidate

Tocris Bioscience | Catalog # 1471

GABA-mimetic; selectively interacts with β2- and β3-subunit containing GABAA receptors
Tocris Bioscience

Key Product Details

Description

GABA-mimetic; selectively interacts with β2- and β3-subunit containing GABAA receptors
View all GABA-A Receptor Modulators »

Product Description

Etomidate is a general anesthetic with GABA modulatory and GABA-mimetic actions; selectively interacts with β2- and β3-subunit containing GABAA receptors. Short acting and potent hypnotic, with low toxicity.

Product Specifications for Etomidate

Molecular Weight

244.29

Formula

C14H16N2O2

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(R)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester

CAS Number

33125-97-2

PubChem ID

667484

InChI Key

NPUKDXXFDDZOKR-LLVKDONJSA-N

SMILES

O=C(OCC)C1=CN=CN1[C@@H]([C@@]2=CC=CC=C2)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
1eq. HCl 12.21 50
Ethanol 24.43 100

Preparing Stock Solutions for Etomidate

The following data is based on the product molecular weight 244.29.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 4.09 mL 20.47 mL 40.93 mL
5 mM 0.82 mL 4.09 mL 8.19 mL
10 mM 0.41 mL 2.05 mL 4.09 mL
50 mM 0.08 mL 0.41 mL 0.82 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 29 publications citing the usage of this product.

Product Documents for Etomidate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Etomidate

For research use only

Related Research Areas

GABA Receptors

Customer Reviews for Etomidate (1)

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  • Would purchase again
    Name: Anonymous
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 07/27/2022
    It came on time, amount was accurate. We would purchase again.
    We purchased this product and used it as anesthesia.

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