General anesthetic with GABA modulatory and GABA-mimetic actions; selectively interacts with β
2- and β
3-subunit containing GABAA
receptors. Short acting and potent hypnotic, with low toxicity.
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The interaction of the general anesthetic etomidate with the γ-aminobutyric acid type A receptor is influenced by a single amino acid.
Belelli et al.
Etomidate: a new intravenous anesthetic induction agent.
Giese et al.
Distinct structural requirements for the direct and indirect actions of the anaesthetic etomidate at GABAA receptors.
Moody et al.
The citations listed below are publications that use Tocris products. Selected citations for Etomidate include:
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