Etomidate

  ( 2 citations )    
Product Datasheet
Catalog Number:1471
Chemical Name:(R)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester
Product Details
Citations (2)
Reviews
Biological Activity
General anesthetic with GABA modulatory and GABA-mimetic actions; selectively interacts with β2- and β3-subunit containing GABAA receptors. Short acting and potent hypnotic, with low toxicity.
Technical Data
  • M.Wt:
    244.29
  • Formula:
    C14H16N2O2
  • Solubility:
    Soluble to 100 mM in ethanol and to 50 mM in 1eq. HCl
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    33125-97-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Etomidate include:

2 Citations: Showing 1 - 2
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  1. Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABAA receptors.
    Authors: Olander Et al.
    Biochem.Pharmacol  2018;150:305
  2. Etomidate Impairs Long-Term Potentiation In Vitro by Targeting α5-Subunit Containing GABAA Receptors on Nonpyramidal Cells.
    Authors: Rodgers Et al.
    Proc Natl Acad Sci U S A  2015;35:9707

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